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It's coming! Now is time for US clinicians to start learning about twice-a-year dosing siRNA therapeutic agent inclisiran, which targets PCSK9 production thereby dramatically improving lipid metrics - https://www.theguardian.com/science/2021/sep/01/gamechanging-heart-disease-drug-approved-for-use-in-england
What "functional medicine" really is - RESPECTFUL INSOLENCE . Please avoid these "functional medicine practitioners." They DO do some positive things but their philosophy and approach overall is seriously flawed. GREAT READ ! :)https://respectfulinsolence.com/2016/12/05/what-functional-medicine-really-is/
Resistance training as a medicine to improve endothelial function - ScienceDirect (both dynamic resistance training and isometric hand grip training contribute to improved endothelial function measured as flow-mediated dilatation of the brachial artery) https://www.sciencedirect.com/science/article/pii/S0021915021012788?dgcid=raven_sd_via_email
Recent publications on Residual Risk : why a lifetime perspective matters. Therapy based on a lifetime benefit approach would increase CVD-free life years substantially more than with risk-factor based treatment https://www.r3i.org/recent-1150
PESA study: elevated triglycerides associate with subclinical atherosclerosis https://www.r3i.org/focus-107
When is it Appropriate to Lower Low Density Lipoprotein-Cholesterol Levels to <30 mg/dL? https://mcusercontent.com/f014b675777f1207ea9bafbf5/files/c0865a3c-3c9e-7b36-4a20-28141355c793/Wong_ND_AJC_Editorial_LDL_C_30.pdf?utm_source=NLA+Master+List&utm_campaign=ea08d05120-%40LIPID_2018_4_4_18_COPY_01&utm_medium=email&utm_term=0_ca7c48644a-ea08d05120-181350197
And lesson one of the month from me is Cholesterol is a 27 carbon sterol molecule synthesized in every cell in the body - there are no good or bad types #cholesterol @society_eas https://twitter.com/EsperionInc/status/1433027364271890433
Today is the first day of #NationalCholesterolMonth! Follow us all month long for exciting #cholesterol content.
. Interesting, but pure speculation/"modeling". Other analyses of REDUCE-IT data by Dr Bhatt et al show that the effect of the mineral oil placebo is at most trivial.
Good discussion of benefit of EPA - recent data mining from Copenhagen Study. Does it "support a more skeptical interpretation of REDUCE-IT's large effect size & should it limit the use of EPA until a second CV outcome trial is performed?" https://www.medpagetoday.com/meetingcoverage/esc/94270?xid=nl_mpt_DHE_2021-08-30&eun=g362180d0r&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%20Top%20Cat%20HeC%20%202021-08-30&utm_term=NL_Daily_DHE_dual-gmail-definition
I really don’t like seeing this Adam. When I came into the league the NFL had a stance against gambling. Now it seems like we’ve accepted it. I realize it’s legal now but we’ve all seen the damage gambling can do to lives. I don’t think we should be promoting it. https://twitter.com/AdamSchefter/status/1432355057136242696
Sign of the times: NFL has reached agreements with FOX Bet, BetMGM, PointsBet, and WynnBET to become Approved Sportsbook Operators for the 2021 NFL season.
Early Harvest Extra Virgin Olive Oil | Kosterina Greek Olive Oil https://www.kosterina.com/ the VERY best EVOO; hi phenol content associated with cardioprotection in the Predimed study !
https://sciencebasedmedicine.org/we-are-not-losing-the-war-on-cancer-belated-2021-edition/?utm_source=rss&utm_medium=rss&utm_campaign=we-are-not-losing-the-war-on-cancer-belated-2021-edition
https://sciencebasedmedicine.org/long-covid-alternative-medicine-sees-a-business-opportunity/?utm_source=rss&utm_medium=rss&utm_campaign=long-covid-alternative-medicine-sees-a-business-opportunity
https://sciencebasedmedicine.org/cognitive-illusions-and-how-not-to-write-about-covid-19-and-children/?utm_source=rss&utm_medium=rss&utm_campaign=cognitive-illusions-and-how-not-to-write-about-covid-19-and-children
https://sciencebasedmedicine.org/genetic-testing-for-selection-of-psychotropic-medications/?utm_source=rss&utm_medium=rss&utm_campaign=genetic-testing-for-selection-of-psychotropic-medications
LDC-Limbo: Lowering to Desired Levels of Cholesterol: Lasting Improvements and Meaningful Benefits Overall https://www.ldl-climbo.org/toc.php
https://twitter.com/i/events/1424408925785317383
WOW - Dr Bill Harris 20 minute interview with 1 of the giants in fatty acid lipidology - Copenhagen's Dr. Jörn Dyerberg was one of the pioneers with Olaf Bang who took their dogsleds to Greenland & evaluated the Inuits - discovered EPA https://www.youtube.com/watch?v=_vTH_aKcrEU @OmegaQuant
Keynote – Atherogenic potential of postprandial lipaemia in diabetes - Triglyceride Forum https://www.triglycerideforum.org/expert-meetings/keynote-atherogenic-potential-of-postprandial-lipaemia-in-diabetes/
Keynote – Remnant cholesterol - Triglyceride Forum https://www.triglycerideforum.org/expert-meetings/keynote-remnant-cholesterol/
Ask a Scientist About T. rex | AMNH https://www.amnh.org/explore/ology/paleontology/ask-a-scientist-about-t.-rex?utm_source=tmatm&utm_medium=email&utm_campaign=210727-MKT-Digital-Resources-Global&utm_term=subscriber&utm_content=version_A&sourcenumber=35979
How Much Exercise Do You Need for Better Heart Health? - The New York Times https://www.nytimes.com/2021/02/17/well/move/exercise-heart-health.html?referringSource=articleShare
Carbs have been vilified & blamed for obesity epidemic, T2D & CVD. But the important role of carbohydrate in a healthy diet is often forgotten. This paper is an excellent review of carbs re wt, IR, T2D, inflammation, lipids, CVD & all-cause mortality. https://www.atherosclerosis-journal.com/article/S0021-9150(21)00146-5/fulltext?dgcid=raven_jbs_etoc_email
2For those who know their lipid biochemistry - These are a collection of very short & funny song parodies written & sung by David Kritchevsky who was also one of the most influential researchers on diet & health of the 20th century. Take a listen at https://www.youtube.com/watch?v=67SIvbIDMFI
Are You a Carboholic? Why Cutting Carbs Is So Tough - The New York Times https://www.nytimes.com/2017/07/19/well/eat/are-you-a-carboholic-why-cutting-carbs-is-so-tough.html?referringSource=articleShare
Another aspect of BASIC cardiometabolic care that too often seems to be ignored, perhaps because it requires getting a urine sample. Too many seem not to know and thus miss the potential early warning sign of a renal/CV issue associated with eGFR < 90 https://twitter.com/ErinMichos/status/1413198630576484355
As this @goKDIGO heatmap indicates BOTH #eGFR & #uACR are prognostic of risk in #CKD. Yet this latest study by @JoeCoresh et al found testing rates for uACR in #T2D are suboptimal and highly variable across organizations. All clinicians need to be onboard! https://care.diabetesjournals.org/content/early/2021/07/02/dc20-2715